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Microbial dysbiosis exacerbates renal fibrosis by increasing the levels of uremic toxins and LPS and by regulating the immune system and inflammatory response

Disclosures: Mohammad AbuAssi: Nothing to Disclose, Dara Suleiman: Nothing to Disclose, Saqr Alsakarneh: Nothing to Disclose, Farah Khraisat: Nothing to Disclose, Talib Al-Abcha: Nothing to Disclose, Harsimran Kalsi: Nothing to Disclose, Tony Brar: Nothing to Disclose, Yaseen Perbtani: Nothing to Disclose 1304 HIGH-THROUGHPUT PROTEOMICS ANALYSIS IDENTIFIES CHANGES IN CIRCULATING PROTEOME SIGNATURES ACROSS DIFFERENT STAGES OF LIVER TRANSPLANTATION SURGERY Xing Li 1 Emily Bethea 1 Leigh Anne Dageforde 1 Katherine Specht 1 Russell Goodman 1 , 1 Massachusetts General Hospital Background: Circulating proteomics, the unbiased global analysis of quantitative protein expression, has been applied to identify the diagnostic and pathophysiologic signatures of various liver diseases such as ALD, MASLD and HCC

Research Suggests Vitamin D Deficiency Is a Risk Factor for Autism Danielle Valletti, Assistant Editor Key Takeaways Children with ASD have significantly lower serum 25-hydroxyvitamin D levels, and early-life deficiency is a strong risk factor for developing ASD