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The study did show a modicum of success, notably that serum MMA levels were reduced, GSH:GSSH ratio increased, and that CoQ10 levels increased, which was presumably due to supplementation, rather than enhanced methylation

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doi: 10.1080/14760584.2022.2022478 174

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The cutaneous defect improves dramatically after fat grafting as evidenced in our case and by other authors.11,12 It is postulated that adipose-derived stem cells can be responsible for this changes.15 The increase of vasculogenesis induced by the grafted fat is another proposed mechanism.16 Conclusion This report shows that fat graft provides a simple, effective and safe correction of corticosteroid induced cutaneous atrophy with very satisfying esthetic and functional results