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J Med Internet Res (2021) 23(7):e27633

The meta-analysis Databases including PubMed, Scopus, Embase, Web of Science, and Google Scholar were searched up to June 2023

Interestingly, relatively little change was seen in the prefrontal cortex of patients, an observation that was also confirmed in a later direct MRS study (133)

they do not represent measured brain neurotransmitter levels

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