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In chemical synthesis, Se in the +4 valence state (e.g., selenite, selenite, or SeO 2 ) is commonly used as a precursor, while reducing agents (e.g., ascorbic acid and glutathione [GSH]) and stabilizers (e.g., chitosan and pectin) are used for the formation and maintenance of SeNPs (244, 245)

Oxid Med Cell Longev 2021(1):6640206 Madkour LH (2019) Function of reactive oxygen species (ROS) inside the living organisms and sources of oxidants

It supports the nervous system by aiding in the formation of myelin, which protects nerve fibres, and it plays a key role in energy production through its involvement in the breakdown of nutrients into usable energy

ImageJ software (ImageJ software, v1.46r, National Institutes of Health, Bethesda, MD USA) was used to analyze these images and to estimate the area percentage (%) of cleaved caspase-3 and GFAP-positive brown immune-stained cells according to Schneider et al

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[DOI] [PMC free article] [PubMed] [Google Scholar] (22).Binkowska AA