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The various forms of injectable B12 have slightly different properties that impact how you might respond: Cyanocobalamin is the most synthesized and stable type but has to convert to active forms

Am J Clin Nutr 2018;108:525-31

This has clinical relevance, as both insulin and free IGF-1 levels are increased in individuals with obesity, and T cells have been found to dominate peripheral inflammation in obesity in human studies, with Th17 cells having a particularly prominent role 30,31,32

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