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doi: 10.1016/j.aca.2017.08.039 80 FloresC

Dassie F

The therapeutic index based upon animal studies is small

Although direct measurement of H 2 O 2 is challenging, oxidative stress can be assessed using indirect biomarkers

It has also been associated to antioxidant functions

It is noteworthy that DBS is not suitable for all patients, as its efficacy and safety are highly dependent on precise target localization, individualized parameter programming, and meticulous postoperative management