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The substrate-binding region (residues 448489), crucial for GS function in S

A pilot study of liposomal glutathione (500-1000 mg/day) showed increased body stores and improved biomarkers of oxidative stress

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Consistent with these findings, Wei et al

This is the first report of a chemical inhibitor of TRI showing antitumour effects via activity on the tumour microenvironment in a mouse model of multiple myeloma