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In the context of diabetes, chronic hyperglycemia overwhelms the mitochondrial electron transport chain, leading to increased ROS production [176]

Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target

These symptoms are not only associated with many chronic diseases

10.1038/cdd.2009.107 Cell Death Differ

For exposure assessment human biomonitoring (HBM) based on the analysis of serum, plasma, whole blood, urine or breast milk samples is a powerful approach which has been extensively used