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Newborn Screening for Vitamin B12 Deficiency in Germany-Strategies, Results, and Public Health Implications. The Journal of pediatrics vol

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Compounders have not shared any data on the new molecule produced from the interaction of tirzepatide and vitamin B12, so we dont know what its safety profile is or whether it could affect how well the medication works, Moreno says

Rare but serious risks include pancreatitis, gallbladder disease, acute kidney injury (secondary to dehydration from GI effects), and a theoretical thyroid C-cell tumor risk based on rodent data that has not been confirmed in human post-marketing surveillance

Inhibiting NNMT has been shown to increase energy expenditure, reduce fat accumulation, improve insulin sensitivity, and normalize glucose tolerance and fasting glucose levels