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Since the developing nervous system and its critical processes rely heavily on the ATP produced by OXPHOS in the mitochondria, the immature brain is critically vulnerable to faults in energy supply [34, 35]

In this study, the oocytes were classified into two types according to the observed mitochondrial distribution pattern: Type I: several mitochondria distributed evenly in the oocyte

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Future studies on the role of oxidative stress in the comorbidity of both diseases should further clarify the nature of these processes, identify common mechanisms involved in the course of diseases, and consider the role of antioxidants in the development of therapeutic strategies

A.Alonso-HearnM.MolinaE.GeijoM.VazquezP.SevillaI

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