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Cytoprotection by prostaglandins in rats: prevention of gastric necrosis produced by alcohol, HCl, NaOH, hypertonic NaCl, and thermal injury

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The synthesis of cysteine relies on the activity of cystathionine -synthase and cystathionine -lyase enzymes

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Such bidirectional control becomes particularly relevant in chronic pain, where thalamic plasticity alters connectivity, excitability, and rhythmicity, leading to thalamocortical dysrhythmia that amplifies nociceptive salience and sustains persistent pain (81, 82)