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Description

Sioud, M

Science 375 (6578), 296301

Atorvastatin attenuates obese-induced kidney injury and impaired renal organic anion transporter 3 function through inhibition of oxidative stress and inflammation

It also supports collagen and reticulin formation and is anti-inflammatory

Data were acquired using Xcalibur software (Thermo Fisher Scientific) and peak areas of metabolites were determined using TraceFinder software (Thermo Fisher Scientific) by identifying metabolites using mass and known retention time following in-house analysis of commercial standards on our systems

Establishing consensus on dosing parameters and administration techniques through standardized protocols is a necessary step toward reproducibility and regulatory approval (Table 5)