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For instance, TfR1 mediates cellular iron uptake, and its upregulation increases iron acquisition, thereby exacerbating ferroptosis

Improved blood sugar control and weight loss in T2D: A 32-week phase 2 trial, involving 92 participants with T2D, revealed that weekly doses of 2.4 mg cagrilintide + semaglutide reduced HbA1c levels by -2.2%, fasting blood sugar by -3.3 mmol/L, and body weight by -15.6% from baseline [12]

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It is characterized by microglial activation and enhanced release of inflammatory factors, such as tumor necrosis factor (TNF-), IL-2, IL-10, IL-4, IL-6, and interferon , which contribute to neuronal injury and death [30, 31]

This benefit can help support a more resilient immune system, especially as we age

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