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More specifically, in the phthalimide part, the phenyl group is solvent-exposed, while one of the carbonyl groups forms the water-mediated hydrogen bond with His359 21

For very hydrophobic peptides the combined ether washes were re-extracted with DMF, allowed to precipitate peptide, and filtered to recover additional peptide

Caspase-1 activates proinflammatory cytokines such as IL-1 by cleaving their respective precursor proteins and proIL-1

Its pathological basis is synovitis, initially manifested as morning stiffness, swelling, and pain in small joints such as hands and feet, which can progress to joint deformities and disability [143]

Montsk, G., Tarjnyi, Z., Mezosi, E

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