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This hypothesis is supported by the causal mediation analysis, suggesting a causal role of HPA-axis function on changes of redox homeostasis in females

Another aspect of barrier function is related to the functioning of multiple active transporters, which carry nutrients and metabolites in both directions ( A second interface between the CNS and periphery, formed by the epithelial cells of the choroid plexus facing the CSF, the CSF per se , and the highly permeable ependyma in the brain ventricles, constitute the BCB (Spector et al., 2015)

Dysregulated signaling pathways involved in tumor drug resistance include the Wnt canonical and non-canonical pathways and the PI3K/PTEN/AKT/mTOR pathway

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Crombie, M

Wohlschlegel, J.A