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Over the past 80 years, risk factors, diagnostic criteria, clinical treatment options, and societal implications of ASD have attracted the concerns of neuroscientists and clinicians (Fig

As we age, our metabolism slows down, which can cause excessive weight gain

Additionally, when outpaced by excessive debris accumulation from intraplaque cell death, efferocytes die, leading to the release of inflammatory DAMPS and unhindered necrotic core formation 2

We observed that more than one-third of metabolites detected in heart were significantly altered with aging, which was predominantly characterized by a rise in the level of glycerophospholids, and to a lesser extent, acylcarnitines (Fig

Likewise, the protein levels of ZnT3 and ZnT6 are markedly and significantly reduced in the spinal cords of ALS patients, while ZnT5 levels show a tendency to decrease, although not significantly

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