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In the past 10 years, ferroptosis, an iron-dependent form of regulated cell death, has become increasingly recognized as an important process that mediates the pathogenesis and progression of numerous cardiovascular diseases, including atherosclerosis, drug-induced heart failure, myocardial ischaemiareperfusion injury, sepsis-induced cardiomyopathy, arrhythmia and diabetic cardiomyopathy

9 By this effect, onabotulinumtoxinA decreases afferent nerve impulses to suppress neurogenic inflammation and prevent peripheral sensitization

10.1534/genetics.107.086041 20 DeRidderB

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Cancers (Basel) (2020) 12(11)

This retrofusion process, in which intraluminal vesicles (ILVs) fuse with the endosomal membrane, is beginning to be elucidated 62,63