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Therefore, this work aims to investigate an in vitro primary astrocyte model by untargeted metabolomics of two cellular subfractions: secretome and intracellular content after pre-defined Aya treatments, based on DMT concentration

americanus hemoglobinase aspartic protease (Na-APR-1) and the heme detoxifying Na-Glutathione S-transferase (Na-GST-1), are currently in clinical trials for a hookworm vaccine, with early results showing the vaccine is safe and immunogenic (Zhan et al., 2010

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