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Reactive oxygen species (ROS) are a key determinant of cancers metabolic phenotype

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Structurally, they can be categorized into four distinct regions: the outer mitochondrial membrane (OMM), the mitochondrial intermembrane space, the inner mitochondrial membrane (IMM), and the mitochondrial matrix, each contributing to the organelles unique and complex functionality ( + to NADH and FAD 2+ to FADH 2 ( Figure 1 )

doi: 10.1126/scitranslmed.3001127 360

Acute intermittent hypercapnic-hypoxia elicits central neural respiratory motor plasticity in humans