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Direct NAD+ supplementation provides a complementary research approach, bypassing the salvage pathway entirely to study the effects of elevated NAD+ on sirtuin activation and cellular metabolism

Note: some secondary sources cite the 2018 Neelakantan Biochem Pharmacol paper under differing PMIDs (29155147 vs 29355482)

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In certain embodiments, the invention encompasses a method of treating Parkinson and related neurological diseases by administering a therapeutically effective amount of one or more cations of the invention

[47] Low vitamin concentrations in human milk occur in families with low socioeconomic status or low consumption of animal products