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We choose t-distributed stochastic neighbor embedding (TSNE) statistical method to visualize the representative genes in a high-dimensional dataset (Figure 2)

Mol Ther (2014) 22:173040.10.1038/mt.2014.125 188 MakIWEvaniewNGhertM

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For example, sequences from the HIV Tat protein (GRKKRRQRRRPPQ) and the Drosophila Antennapedia protein (RQIKIWFQNRRMKWKK) have been found to be capable of functioning as delivery peptides: A peptide or peptidomimetic can be encoded by a random sequence of DNA, such as a peptide identified from a phage-display library, or one-bead-one-compound (OBOC) combinatorial library (Lam et al., Nature, 354:82-84, 1991)