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Due to its ability to stimulate IL-1 secretion, the NLRP3 inflammasome has been linked to IBD in experimental models as well as human studies (191)

(JPG 413 kb) Supplementary Figure 3 (download JPG This figure shows the vectors used in the lentivirus-mediated gene transfer, as well as immunohistochemistry and in situ hybridization pictures of lentivirus-injected brain

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The metabolic products are absorbed by the body or help in resisting CVDs and exhibit certain biological activities

Oligodendrocyte precursor cells ingest axons in the mouse neocortex

Transferrin receptor 1 (TFR1) expression in macrophages is induced by the activation of this pathway, which in turn increases iron uptake and promotes intracellular survival of bacteria