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R 1a , R 2 , R 3a , R 4a and R 5a are independently selected from the group consisting of H, and C 1-4 alkyl

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The G6PD molecule has two NADP + binding sites including a structural NADP + binding site and a coenzyme NADP + binding site (Kotaka et al., 2005)

Front Biosci (Landmark Ed) 29(8):306

Vitamin C is a mandatory cofactor for the enzyme dopamine beta-hydroxylase, which is responsible for converting the neurotransmitter dopamine into norepinephrine