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Mechanistically, these effects converge on autophagy-related nodes, including the PI3K/AKT/mTOR, AMPK/TFEB, PINK1/Parkin, ULK1/Beclin-1/VPS34, p62/Nrf2, IB/NF-B, and miR-375-3p/ATG2B/PTEN/AKT pathways (Tables 13)

In an effort to understand the mechanism behind how GENUS rescued the strong CPZ phenotype, we conducted brain proteomics

In hepatic lipid metabolism studies, it is used to explore regulatory mechanisms and intervention strategies for hepatic steatosis

Methylation biochemistry involves a complex series of chemical reactions in the body that are essential for DNA regulation, neurotransmitter production, and antioxidant protection