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Senescence associated SA--Gal activity SA--Gal staining was conducted with -Galactosidase Staining Kit (Beyotime, China), following the protocol in reference [29]

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While traditionally utilized in the management of cardiometabolic conditions like type 2 diabetes and dyslipidemia, these compounds are increasingly recognized for their profound ability to activate cellular energy sensors, neutralize oxidative stress, and support the healing of the vascular endothelium