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Therefore, it is likely that inflammatory cytokines play a role in pregnancy failure by increasing fetal ferroptosis, and conversely, anti-inflammatory cytokines act to reduce fetal ferroptosis and promote successful pregnancy

Metabolic modulators such as antioxidants, metformin, and melatonin also show potential by modulating mitochondrial and immune pathways

Deletion of DDB1-and CUL4-associated factor-17 (Dcaf17) gene causes spermatogenesis defects and male infertility in mice

Chen et al., 2012

Similar content being viewed by others Introduction Musculoskeletal (MSK) disorders are highly prevalent and one of the most common health concerns for working-age individuals seeking healthcare services 1,2