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APA significantly impacts human pathogenesis by influencing mRNA stability, localization and translation, thereby affecting the expression and function of crucial genes

The keloid tissues for organ culture were firstly incubated in a DMEM containing 10% FBS at 37 C for 24 h, and the medium was replaced by the DMEM containing 2% FBS, the final concentration of 25 M FOXO4-DRI was added in the medium immediately

doi: 10.1038/mp.2015.182 116 CampbellDBSutcliffeJSEbertPJMiliterniRBravaccioCTrilloSet al

J Biol Chem 282:2399624003 Sierra-Rivera E, Summar M L, Dasouki M et al

Moreover, TSA reduced cardiac hypertrophy in SHRs by inhibiting the Cys-C/Wnt signaling pathway, decreasing protein expression of Cys-C, Wnt2, -catenin and WISP-1 (107)

40(12):BSR20201006 Zhu F, Zhang Q, Feng J, Zhang X, Li T, Liu S et al (2023) beta-Glucan produced by lentinus Edodes suppresses breast cancer progression via the Inhibition of macrophage M2 polarization by integrating autophagy and inflammatory signals