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These findings support the conclusion that R-loop-mediated fork stalling induced by oncogenic RAS is a consequence of ROS-induced dissociation of the TIMELESS-TIPIN complex from the replisome, which slows down replication fork progression

Studies indicate that individuals with lower B12 levels are more likely to be obese[2], even after accounting for factors like diet, lifestyle and medication use

Hossain, M.A

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Although existing studies have elucidated the genetic basis of IMF deposition in chickens from the perspectives of interspecific and intraspecific differences, several limitations remain: 1) Current genetic mechanism studies have predominantly focused on specific genes or pathways (e.g., FABP4 and PPAR), yet they lack systematic integration of multidimensional regulatory networks (e.g., the interactions among SNPs, epigenetic modifications, and noncoding RNAs (ncRNAs))

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