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36,49 The latest research indicates that TMAO can impair -cell function and glucose tolerance, and the mechanism may be related to the promotion of -cell ERS, dedifferentiation, and apoptosis

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(B) Cells were stained with mouse anti-p230 with AlexaFluor-555 conjugated anti-mouse secondary (red), and EdU-labeled vDNA was stained with Click-iT EdU AlexaFluor-488 (green)