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Research indicates that three groups that should avoid TB4 and TB-500 are: Those who are pregnant or breastfeeding: The safety of these peptides hasnt been established in pregnant or nursing individuals

Most side effects in this combination come from tirzepatide, not AOD 9604

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Others stop immediately without issues

Blunted or impeded therapeutic response to vitamin B12 may be due to such conditions as infection, uremia, drugs having bone marrow suppressant properties such as chloramphenicol, and concurrent iron or folic acid deficiency