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One study found a positive correlation between CCS expression and survival in ALS patients, suggesting that higher CCS expression may prolong survival and confer protective effects in ALS pathogenesis (123)

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However, excessive loading causes re-injury

Reduced butyrate levels in CFS/ME patients may contribute to increased gut permeability (leaky gut), allowing microbial products like LPS to enter the circulation and trigger systemic immune activation (Wang J.-H

Notably, a more pronounced dose-response effect was observed in individuals with longer durations of night shift employment [40,41]