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S2) demonstrated the minimal tumor volume, lowest tumor weight, and maximum survival time, confirming the superior therapeutic efficacy of the combined administration of DOX, Zn 2+ and Nrf2 siRNA (Fig

[cited 2021 Nov 24] 28

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This pathway is initiated by a combination of Patched and Hh proteins, consisting of Sonic Hh (Shh), Desert Hh, and Indian Hh (Ihh), which allows Smoothened to transmit signals to the nucleus

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