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Mutations in the ORF3a protein, such as T223I and S171L abrogated induction of LDs and led to deficient replication and lower virus yield in vitro (Wang et al., 2023)

Inadequate power or unobserved confounding effects would contribute to the lack of association

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doi: 10.1016/j.nut.2018.11.015 178 WeberATShahNDSaukJLimketkaiBN