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A slight but significant increase of coumarin-6 uptake by ischemic brains of mice was observed with GSH coated PLGA-PEG nanoparticles when compared with non-GSH coated PLGA-PEG nanoparticles [51]

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Astaxanthin, due to its potent antioxidant properties, helps maintain cellular redox balance, inhibits tissue inflammation (Ohgami et al., 2003), and reduces the expression of pro-inflammatory factors such as IL-15 , IL-10 , TNF- , CASP3 , and CASP9 (Song et al., 2017), thereby alleviating cell damage from excessive inflammation