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Isoniazid (INH), as an anti-tuberculosis drug, damages the liver and induces lipid peroxidation leading to apoptosis of liver cells through glutathione depletion (175)

Targets for clear cell renal cell carcinoma include the NF-B agonists IB kinase b and caspase recruitment domain protein 9 (CARD9), MAPK1, fibronectin, collagen IV, RpB1 (the large subunit of RNA polymerase II), human antigen R (HuR), and Akt (also known as protein kinase B)[62]

NAC (N-Acetyl Cysteine) at 600-1200mg daily and TUDCA (Tauroursodeoxycholic acid) at 250-500mg daily provide meaningful hepatic protection

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