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OMM permeabilization is regulated by the Bcl-2 family of proteins, and the mitochondrial protein cyt c is subsequently released into the cytosol to activate caspases and initiate apoptotic cell death [101,102]

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It is a quinolinium salt substituted at position 5 with an amino group and at position 1 with a methyl group

As an antidote to acetaminophen poisoning, NAC restores the hepatic GSH pool depleted in the drug detoxification process

The opposing effects of mTOR signaling on apoptosis may depend on the distinct pro-apoptotic stimuli

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