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Another HLA risk allele identified in genome-wide association studies is the rs2476601 variant in the PTPN22 gene, which is associated with an increased risk of DILI from multiple drugs

This is probably due to the fact that network activity results from the synchronized activation of all excitatory synapses at the same time, and as a consequence, modulations are detected mainly by changes in the frequency of burst occurrence

Sikiric P, Seiwerth S, Rucman R, Kolenc D, Vuletic LB, Drmic D, et al

These findings identify a novel mechanism for ACs anticancer effects in glioblastoma, highlighting its potential as a therapeutic agent by suppressing EMT and tumor aggressiveness through ubiquitin-mediated degradation of c-Met (Hei et al

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Local refinement of mTORRHEBMLST8 (359,012 particles after symmetry expansion) and RAPTORRAGRagulator (189,975 particles after symmetry expansion) yielded maps of 3.12 and 2.98 , respectively