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Total cholesterol levels at the end of our study in the control DIO mice were comparable to cholesterol levels reported by the vendor for age-matched DIO mice

BV, alone or in combination with other compounds, significantly increased apoptosis (as indicated by upregulation of the pro-apoptotic marker Bax and downregulation of the anti-apoptotic marker Bcl-2) and decreased the mRNA level of the BC-related receptors ER and EGFR in the two BC cell lines T-47D and MCF7 [40]