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Enzymatic glutathione production using metabolically engineered Saccharomyces cerevisiae as a whole-cell biocatalyst

These pyrethroids induce a more pronounced prolonged opening of the VGSC, resulting in a much longer period of influx of sodium ions that can last from several seconds to minutes [115, 116]

Biochim Biophys Acta 1488:167181 Orr WC, Radyuk SN, Prabhudesai L, Toroser D, Benes JJ, Luchak JM, Mockett RJ, Rebrin I, Hubbard JG, Sohal RS (2005) Overexpression of glutamate-cysteine ligase extends life span in Drosophila melanogaster