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Evolution of the metazoan TrxR appears to have been brought about by extension of the C-terminal protein coding sequences of the gene, leading to acquisition of the new C-terminal active site (Novoselov and Gladyshev, 2003)

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Despite their benign nature, they are able to undergo rapid and significant growth (Stewart, 2001

Genome-wide crispr screening identifies Dck and Ccnl1 as genes that contribute to gemcitabine resistance in pancreatic cancer

doi: 10.1021/acs.chemrestox.4c00348 91 VallergaCLZhangFFowdarJMcRaeAFQiTNabaisMFet al