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Abbreviations A.A: Acetic acid DAI: Disease activity index DSS: Dextran sulphate sodium IBD: Inflammatory bowel disease JAK-STAT: Janus kinase/signal transducers and activators of transcription NF-B: Nuclear factor kappa B Nrf2: Nuclear factor erythroid 2related factor 2 NLRP3: Nucleotide-binding domain, leucine-richcontaining family, pyrin domaincontaining protein-3 NO: Nitric oxide synthase PPAR-: Peroxisome proliferator-activated receptor gamma TLR: Toll like receptor TNBS: 2, 4, 6-Trinitrobenzene sulfonic acid UC: Ulcerative colitis References Buie MJ, Quan J, Windsor JW, Coward S, Hansen TM, King JA, Kotze PG, Gearry RB, Ng SC, Mak JW, Abreu MT

It also depends on how the patient responds to the initial therapy

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doi: 10.2135/cropsci2011.06.0296 26 ChandrasekaranJ.BruminM.WolfD.LeibmanD.KlapC.PearlsmanM.et al