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PyMT mice were calculated by KaplanMeier survival curve comparisons, as well as the P values derived from log-rank test

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Berberine Protects Immortalized Line of Human Melanocytes from H2O2-Induced Oxidative Stress via Activation of Nrf2 and Mitf Signaling Pathway

238,242 Isocitrate dehydrogenase 3 (IDH3), a pivotal rate-limiting enzyme in the TCA cycle, is downregulated, leading to oxidative phosphorylation uncoupling and lactate accumulation in the brains of AD patients and AD transgenic mice