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doi: 10.1016/j.tem.2008.07.005

A single-center RCT demonstrated the anti-atherosclerotic activity of alogliptin in 66 patients with dysglycemia and acute coronary syndrome

This treatment significantly alleviated deficits in social interaction, anxiety, and repetitive behaviors

CHOP expression and phosphorylation of eIF2 and JNK modulate Ca 2+ flux between the mitochondria and the ER, modulating mitochondrial metabolism and inducing the opening of mPTP and activation of apoptotic pathways