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This HPA axis co-stimulation is dose-dependent and has been characterised in both healthy subjects and patient populations, including studies in children with idiopathic short stature undergoing GH stimulation testing

doi: 10.1172/JCI143777 61 HeM.WeiW.ZhangY.XiangZ.PengD.KasimumaliA.et al

Khan R, Krishnakumar A, Paulose CS (2008) Decreased glutamate receptor binding and NMDA R1 gene expression in hippocampus of pilocarpine-induced epileptic rats: neuroprotective role of Bacopa monnieri extract

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If anything other than sterile saline was added, it may have been a preservative that you had reacted to

Although the role of TGF-1 in the context of obesity-induced airway fibrosis in asthma remains elusive, and one study observed no difference in serum levels of TGF-1 between individuals with asthma and obesity compared to healthy controls (243), the role of TGF-1 in the context of obesity-induced airway fibrosis should be considered