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N Engl J Med 323 : 16 Taaffe DR et al

The neurites lose their way

These results suggest that ceramides and ASM coordinate mitochondria and autophagosome membrane formation assisting mitophagy (Figure 2)

The cold chain should be maintained from the time of compounding through dispensing and patient storage to ensure optimal medication quality

In this review, we summarize the role of GM in the pathogenesis of OP based on the latest understandings, and highlight the promising potential of strategies targeting GM for the intervention and management of OP