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The approval, a third indication for Blincyto, was supported by the Phase III E1910 clinical trial, in which Amgens drug plus multiphase consolidation chemotherapy showed superior overall survival versus chemotherapy alone

Ocrelizumab was superior to natalizumab and alemtuzumab on relapses in patients who were not treatment-nave, experienced disease activity on the prior therapy or stopped prior therapy due to lack of efficacy

Apatinib and s-1 (tegafur + gimeracil + oteracil potassium) have been approved by the National Medical Products Administration (NMPA) of China for the treatment of GC, and patients can afford these treatments (131)

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However, further research with large-scale clinical trials is needed to validate its productivity, safety, and long-term results in humans before widespread medical usage can be recommended

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