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Furthermore, additional mechanisms are reported to regulate GLS, such as RNA-binding protein regulation of alternative splicing [68,69] or protein degradation through the ubiquitin ligase complex APC/C-Cdh1 during cell cycle progression [70]

To gain greater insight into the specific sequence-structure-function relationships among GUS proteins, particularly those belonging to the L1 class, we generated a sequence similarity network (SSN), which groups protein sequences into clusters and facilitates the analysis of functional relationships within protein families 24

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This measure was reported in previous studies to have a reliable and linear relationship to the molar abundance of a compound in a sample (Tarasov et al., 2014)

Early embryonic lethality of mice lacking ZO-2, but not ZO-3, reveals critical and nonredundant roles for individual zonula occludens proteins in mammalian development