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Glutathione helps maintain the body's natural antioxidant balance by participating in systems that neutralise oxidative stress at the cellular level

These enzymes catalyze the conjugation of glutathione with various toxins, including: Pesticide residues Industrial chemicals Alcohol metabolites Prescription drug byproducts Step 3: Sulfation Support Glutathione provides sulfur groups needed for sulfation, another crucial phase II detoxification pathway

Factors such as poor nutrition, chronic stress, exposure to environmental toxins, and the natural aging process can deplete glutathione (Cymbiotika, 2025)

Different depression phenotypes may yield conflicting results, and certain clinical features of MDD influence these pathways [10]

Immunohistochemistry staining Tissue sections were deparaffinized in xylene and rehydrated

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