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In animal studies, doses are typically scaled by body weight at approximately 110 mcg/kg

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323,324 The influential role of ALOX12, ALOX15, and 12-HETE on diabetes progression is also correlated with NOX (nicotinamide adenine dinucleotide phosphate oxidase)-mediated endoplasmic reticulum stress, TRPV1 activity, and MAPK signaling, ultimately leading to cell apoptosis

106,107 This context-related involvement in CRPC may also apply to MCL1, whose mRNA levels, like BCL-2, anti-correlated with the AR-A in 3 (Rajan, Sharma and Long) datasets (supplementary Fig

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