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The mechanistic literature on GHK-Cu in primary human dermal fibroblasts and skin-explant models has typically used GHK-Cu concentrations in the nanomolar to low-micromolar range, with biological effects on collagen synthesis, fibroblast proliferation, and gene expression reported at sub-toxic concentrations

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10.2147/DDDT.S284163 103 XingweiX.XinG.PengZ.TaoF.BowenD.XiaomingK.et al (2014)

Ferritin, typically found in the cytosol can also be secreted, providing an additional iron source

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Our body synthesizes glutathione through a multi-step process